Deep brain stimulation — a novel surgical procedure — is emerging as a treatment of last resort for people diagnosed with neuropsychiatric disorders such as severe obsessive-compulsive disorder. The US Food and Drug Administration granted a so-called humanitarian device exemption to allow patients to access this intervention, thereby removing the requirement for a clinical trial of the appropriate size and statistical power. Bypassing the rigors of such trials puts patients at risk, limits opportunities for scientific discovery, and gives device manufacturers (...) unique marketing opportunities. We argue that Congress and federal regulators should revisit the humanitarian device exemption to ensure that it is not used to sidestep careful research that can offer valuable data with appropriate patient safeguards. (shrink)

Nucleation and motion of kink pairs on partial dislocations are examined by elasticity theory for materials with a high Peierls stress. Two approaches are used: one considers the change in average stacking-fault energy due to alloying elements and the other considers the change in local SFE due to a nearby solute atom. Both approaches highlight the role of SFE on kink nucleation, propagation and annihilation and both furnish strain rate as a function of stress, temperature and SFE. Model predictions are (...) compared with yield stress data for two systems: firstly, an intermetallic, MoSi 2 , which softens for alloying elements that decrease the SFE and hardens for Re additions that increase the SFE; secondly, a ceramic oxide, MgO-Al 2 O 3 spinel, which softens with increasing addition of excess alumina and at the same time exhibits a decrease in SFE. The average SFE approach agrees qualitatively with the data while quantitative agreement is obtained with the local SFE approach. The possibility is considered that the model applies to other materials, such as TiAl, HfV 2 and Fe 3 Al, which show softening with certain alloying additions. One requirement is that the dislocations are dissociated more than a few atomic distances; otherwise kink nucleation occurs on the perfect dislocation . Hence the model does not apply to materials such as bcc metals which only have a core dissociation. Normal hardening effects of solutes from size and modulus misfits are additive with any softening effects from a decrease in SFE and so may mask the latter, as occurs for W additions to MoSi 2. (shrink)

The introductory revised essay, "Horses of Wrath: Recent Critical Lessons," followed by nine reprinted essays, pits the Christian Rationalist, Wimsatt, an aroused Horse of Instruction, against the Tigers of Wrath, Blakean Myth critics led by Northrop Frye. Their battleground is the relation of poetry to life: what for the Blakeans is the fearful symmetry of poetry as the apocalypse of life is for Wimsatt the hateful siege of contraries, both an anarchy of life and a confusion of poetic limits. Wimsatt (...) supports the classical and Christian notion that harmony comes "in spite of" the conflict of good and evil, not "because of" that conflict, as the Blakeans would claim. For Wimsatt, poetry's unique kind of cognition is the analogous perspective it establishes toward contraries, namely the perspective of drama and metaphor in which is created a mock substance of the human condition. But after Wimsatt's analysis, we are left with a dualism which can be itself a hateful contrary: the more poetry performs its perspective function, the more it destroys its subject matter. It is also to the credit of Wimsatt's theoretic hesitancy that he will not let us forget these contraries.—E. S. T. (shrink)

‘The tale of the Argonauts was among the most popular myths in Greek and Roman literature of all periods.’ There was, however, not inconsiderable variation in certain aspects of the narrative: in the inclusion or exclusion of entire episodes; in (un)expected divergences from more authoritative versions of the story; and in the details of minutiae. In the Argonautic choral odes of Seneca'sMedea(301–79 and 579–669), and in Valerius Flaccus’ incomplete epic, there is a conspicuous, learned engagement with much of the earlier (...) tradition that hints at versions of the myth which are divergent from those that the two poets privilege in their respective narratives. Such moments serve to assert the playwright's and the epicist's status asdocti poetae, and to engage the learned reader in a (re)negotiation of the tradition; at times, an awareness of a literary past seems to be given to particular characters too so as to heighten the reader's experience of the narrative—by a sort of prolepsis—as it unfolds. (shrink)

The article is devoted to the significance of the irrational in education processes and to the role of teacher as an actor of psychological influence on the formation of child’s personality. Unfortunately, teacher education programs at universities do not properly introduce to the students all the aspects (including unconscious ones) of the interaction between people, in particular in the “teacher – student” system. At the same time, in the pedagogical literature there are no special works related to this issue. Psychological (...) theories and methods of education, which are designed to form and develop a personality, can simply destroy the necessary qualities in a child that lead to his independence and self-affirmation. Teachers who are incompetent in pedagogical issues often defend themselves by appealing to the well-known names of scientists and their theories. The theories should not become a dogma and a main path in education. They should serve as an auxiliary instrument. The theory of education is obliged to revise the content and form of the organization of educational process in accordance with the understanding and sense of the rhythm of the New World, taking into account the integration of educational concepts that provide a balance of the rational and irrational in the cognitive activity of a student. This balance is necessary for the full and comprehensive development of child’s personality, for the formation of his/her identity. The author of the article believes that under the conditions of large-scale simulacrization, virtualization, digitalization of the educational space, it is necessary to strengthen the emotional component of the educational process to avoid the final elimination of the aura (W. Benjamin) of the class area from the sphere of human relations in the “teacher – student – teacher” system. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:BOOK REVIEWS 265 concluding chapter (pp. 150-52), Dr. Clair deals with "Comment lire l'oeuvre du P. Thomassin," providing much guidance to anyone who wishes to avail himself of the rich resources in Thomassin's writings. From the point of view of the history of philosophy, the most interesting aspects of Thomassin's thought seem to be (1) his "Cartesianism," that is, the extent to which he early imbibed Descartes' new ideas, (...) and played a role in the fusion of the views of Augustine, B6rulle, and Descartes that developed in the Oratory, (2) his attempt to find a viable theory of the nature of Grace somewhere between Arnauld and Malebranche, and (3) his efforts to formulate a philosophy of history within an Augustinian theology; a philosophy of history that would make historical research and understanding of genuine philosophical and religious value to man. Dr. Clair's too brief discussions indicate that Thomassin was definitely influenced by reading Descartes, but also that Thomassin was much too eclectic to be a Cartesian. With regard to the problem of Grace, where the Cartesian Arnauld fought with the semi-Cartesian Malebranche, Thomassin tried deftly to maintain an Augustinian position that was not quite as rigid as that of the Jansenists, nor as moderate as that of Malebranche (though Arnauld tried to use Thomassin's erudition and authority in his battles with Malebranche). Unfortunately Dr. Clair does not try to evaluate whether Thomassin really found a coherent and theologically acceptable middle-ground between the two antagonists. On the subject of the philosophy of history, Thomassin's views seem most interesting (at least to this reviewer). The short text that Dr. Clair includes on the difference of history from science reveals Thomassin trying to show that the investigation and comprehension of temporal particulars can have significant value for man's understanding of man and that there can be genuine certainty about past facts. Thomassin was writing in the period when modern historical method and outlook were born, when historical study changed from chronicles and ammunition in theological and political disputes to a basic way of understanding human nature. Those concerned with the role of Bayle, Hume, Gibbon, and Vico in developing an historical methodology and a rationale for art historical approach to human problems might well profit from considering Thomassin's writings in this area, and the influence they had on modern historiography and philosophies of history. Dr. Clair's short work certainly helps in filling a lacuna in our picture of the seventeenth century. It also makes one wish he had done more, and had provided a "complete" study of Thomassin's thought and influence. That, perhaps, is one of the major purposes of this new series, in that it will lead scholars to looking into the more hidden portions of the period, and will lead them to filling out in more detail and depth the history of the rise and fall of modern philosophy. It is to be hoped that future volumes in this series will continue to whet our appetites for further investigations, and will transform more of the names we run across into figures about whom we have some information and from whom we can still learn something. RICHARD H. POPKIN University of California, San Diego Berkeley's Theory of Vision..4 Critical Examination of Bishop Berkeley's Essay towards a New Theory of Vision. By D. M. Armstrong. (Melbourne: University Press; London and N. Y.: Cambridge University Press, 1960. Pp. viii + 106. $4.50). Berkeley's brilliant though disconcerting Essay has been rather neglected for some time, except for the able studies of C. M. Turbayne of Rochester University (N. Y.). Armstrong's book is welcome for that reason, also for its freshness, clearness, and rich brevity. A1- 266 HISTORY OF PHILOSOPHY though a slim volume, it is packed with close yet lucid argumentation, conducted throughout with good manners, and throughout exploratory, clarifying problems, exposing logical and empirical difficulties, not grandly telling us what the truth is but leaving us in a better position to carry on the exploration ourselves. It is an exemplary piece of philosophical discussion. He clears his ground by noting that the Essay, so far as... (shrink)

Using covariant derivatives and the operator definitions of quantum mechanics, gauge invariant Proca and Lehnert equations are derived and the Lorenz condition is eliminated in U(1) invariant electrodynamics. It is shown that the structure of the gauge invariant Lehnert equation is the same in an O(3) invariant theory of electrodynamics.

The following notes on the In Pisonem are largely based on the commentary of R. G. M. Nisbet . The references to the speech are by section and line of his text, and where my note is based on one of his I add a reference to the page of his commentary. 1. 20 voltus …, qui sermo quidam tacitus mentis est: ‘thoughts are usually revealed by the face.’ Add to Otto's, Seyffert-Muller's, and N.'s examples: Curtius 8. 6. 22 ‘voltus (...) haud sane securi animi index’, Juv. 9. 18 ff. (shrink)

Brodtkorb's "phenomenological reading" discusses the conceptually resistant realities, "World," "Body," "Others," and "Time," as they are interpreted in Moby Dick, and are focused by Melville in the inscrutable meaning of the white whale. "Mediation" is the key to interpretation, and, thus, the hero of the novel is Ishmael, who understands that the whale's meaning is constituted anew by each perceiver; Ishmael's mental life is a succession of attitudes—a series of "incantations"—which matches existence as process. From this phenomenological point of view, (...) Ahab's rigid interpretation of the whale as an allegory of divine malevolence is doomed, since allegory is a static mediated category, untrue to process. Yet this processional epistemology is itself in doubt if, as Brodtkorb admits, the uncertainty of the inscrutable is itself in question; and this doubt allows for the potential correctness of even Ahab's reductive allegorization. Thus, while Brodtkorb's phenomenology is a very sensitive instrument for indicating the shifting meanings of Melville's world, the final relation of potentially correct and incantatory concepts to this world is weakly conceived, due to the weakness of the instrument itself.—E. S. T. (shrink)

The fact that the enclosing word order is not common in Latin prose, and is first found to any extent in the neoteric poet Catullus and in Cicero's Aratea, raises the possibility that they may owe this feature of their style to Alexandrian influence. In one way at least, in the inversion of connecting particles, atque, nam, etc., Alexandrian influence on Catullus' word order is generally admitted, e.g.

The article presents the main results of theoretical review on the study of the phenomenon of affect and definition, classification, legal aspects of affective states, as well as the results of statistical processing of data on crimes in the state of affect are provided in Kazakhstan for the last 5 years according to the provided statistical data from the database of the General Prosecutor's Office of the CLSaSA (Committee on Legal Statistics and Special Accounts) of the RK. The relevance of (...) this study is the study of the phenomenon of affect in Kazakhstan, as well as the processing of statistical data on affective suicide, as little-studied and not sufficiently developed phenomena. It is important to note the difference in approaches to understanding the term physiological affects (PA), which actually has no direct analogue in the English-language bibliography. In some respects, the concept of an "irresistible impulse" based on passion corresponds to it. Both conditions can significantly affect a person's behavior and their ability to control their actions, while both can serve as mitigating circumstances in law. At the same time, physiological affect is usually short-lived and characteristic of sane individuals, while an irresistible impulse can be a chronic condition associated with a mental disorder. Subsequent research may be devoted to the issues of comparing the two above concepts from a forensic perspective. (shrink)

Catalepton 10 is a unique survival from antiquity: it is the only parody of an entire poem to reach us, and is written in pure iambic trimeters, a near intractable metre. Addressed to Sabinus, an upstart muleteer, the poem launches a stinging attack at him, and draws attention to his status as a parvenu. It remains incredibly close to its charming model—Catullus 4 —in structural, lexical, stylistic and metrical terms, but rather different in purport. In attempting to reassess a number (...) of problems in the text of the poem, the textual critic ought largely to be guided by the relationship of Sabinus ille to its model, as it is clear that the author of Catalepton 10 was an incredibly close reader of the Catullan text and sought not only to imitate through parody but also to subvert and deflate his predecessor's poem. (shrink)

The Ehrenfest paradox is reviewed in order to categorize classes of “resolution” that are logically at least semiconsistent. Cantoni's candidate is analyzed with reference to such a taxonomy of resolutions.

One of the most important theoretical and ideological tasks of Marxist philosophy is the critical study of the philosophical thought of the West. In the second half of the 1970s and beginning of the 1980s, the ideological struggle on the international arena entered a new stage. It was characterized by the turn of the forces of imperialist reaction away from the politics of detente to the politics of the "cold war," to the active opposition to the forces of peace, democracy, (...) and socialism. The struggle of ideas has swung back and forth in the context of, on the one hand, a resurgence of reactionary anticommunist tendencies, and the stimulation and expansion of antimilitary movements and the struggles of the peoples for peace and socialism on the other. (shrink)